Atypical Cristae Morphology of Human Syncytiotrophoblast Mitochondria
نویسندگان
چکیده
منابع مشابه
Atypical cristae morphology of human syncytiotrophoblast mitochondria: role for complex V.
Mitochondrial complexes I, III(2), and IV from human cytotrophoblast and syncytiotrophoblast associate to form supercomplexes or respirasomes, with the following stoichiometries: I(1):(III(2))(1) and I(1):(III(2))(1-2):IV(1-4). The content of respirasomes was similar in both cell types after isolating mitochondria. However, syncytiotrophoblast mitochondria possess low levels of dimeric complex ...
متن کاملMitochondria: Organization of Respiratory Chain Complexes Becomes Cristae-lized
For over 100 years mitochondria have been known for their distinctive morphology featuring elaborately folded cristae, and their role as 'the powerhouse of the cell'. New research shows that these two characteristics are more dependent on each other than previously thought.
متن کاملParacrystalline arrays in atypical cristae and mitochondrial division.
Paracrystalline arrays in atypical cristae were observed in a few large mitochondria in the process of replication, in the follicular cell of the normal and gonadectomized rabbit thyroid gland. They were about 30 nm in diameter and spaced approximately 35-40 nm apart, and oblique sections showed parallel arrays which had a pitch of 25 nm. The number of inclusions varied in number and were simil...
متن کاملComparative morphology of rodent vestibular periphery. II. Cristae ampullares.
We made flattened neuroepithelial preparations of horizontal and vertical (anterior and posterior) cristae from mouse, rat, gerbil, guinea pig, chinchilla, and tree squirrel. Calretinin immunohistochemistry was used to label the calyx class of afferents. Because these afferents are restricted to the central zone of the crista, their distribution allowed us to delineate this zone. In addition to...
متن کاملAPOOL Is a Cardiolipin-Binding Constituent of the Mitofilin/MINOS Protein Complex Determining Cristae Morphology in Mammalian Mitochondria
Mitochondrial cristae morphology is highly variable and altered under numerous pathological conditions. The protein complexes involved are largely unknown or only insufficiently characterized. Using complexome profiling we identified apolipoprotein O (APOO) and apolipoprotein O-like protein (APOOL) as putative components of the Mitofilin/MINOS protein complex which was recently implicated in de...
متن کاملذخیره در منابع من
با ذخیره ی این منبع در منابع من، دسترسی به آن را برای استفاده های بعدی آسان تر کنید
ژورنال
عنوان ژورنال: Journal of Biological Chemistry
سال: 2011
ISSN: 0021-9258
DOI: 10.1074/jbc.m111.252056